![]() ![]() Full support of sequence data confidence values.Comprehensive DNA sequence editing tools.Multiple, configurable DNA assembly algorithms.Sequencher capabilities include heterozygote & SNP detection and analysis, cDNA to Genomic DNA large gap alignment, comparative sequencing, support for confidence scores, ORF translation, GenBank feature import, and restriction enzyme mapping. Life Science researchers use Sequencher for many diverse DNA sequence analysis applications including de novo gene sequencing, mutation detection, forensic human identification, systematics, and more. ![]() Last but not least, the program is able to underline all ambiguous bases, highlight bases that have been edited, and you can also select a background colour, and export the information to CSM.Īll in all, Sequencher comes packed with configurable DNA assembly algorithms, DNA sequence editing tools, and other useful features for helping users analyse DNA sequences and contigs in a professional way.Sequencher was designed to work with all automated DNA sequencers and is widely known for its lightning-fast contig assembly, short learning curve, user-friendly editing tools, and superb technical support.įirst released almost 15 years ago, Sequencher is currently used for sequence analysis tasks in every major genomic and pharmaceutical company as well as numerous academic and government labs in over 40 countries around the world. Other important features worth mentioning enable users to view and print a report, use the chromatogram for editing the contigs, create restriction maps, find items by applying different filters, and copy the information to the Clipboard or print it. It is possible to analyse the differences between sequences and contigs, and it proves to be pretty useful especially for SNP analysis, mutation detection, and clone checking options. Plus, you can set up conditions by configuring the dedicated algorithms and parameters, opt for an automatic assembly mode, edit, move, or delete bases and sequences, insert gaps or bases, and create a new sequence from a consensus. ![]() set base numbers, find ambiguities, use voice verification to check base calls). Sequencher allows users to remove one sequence or multiple ones, rename a sequence or contig, automatically save the projects at preset time intervals, as well as perform basic sequence editing operations (e.g. This way, you can cut ambiguities and low confidence data. ![]() Plus, it gives users the possibility to insert information from various file formats, namely ABI, MegaBase, CEQ, SCF, GenBank, EMBL, DDBJ and plain text files.įurthermore, there are several dedicated tools designed to help you trim poor quality data or vector contamination from your sequences. When it comes to importing files, you can drag and drop them directly into the primary panel, or use the copy and paste commands. The application gives users the possibility to create a new project by assembling the DNA algorithms, and creating new sequence fragments and templates. The layout is not very intuitive and rookies may spend some trying to configure the dedicated parameters. Sequencher is a Windows utility built specifically for helping users manipulate DNA sequencers and contigs. ![]()
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